465119
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465119
Aldrich
Baicalein
98%
| Synonym: | 5,6,7-Trihydroxyflavone |
| CAS Number: | 491-67-8 |
| Linear Formula: | C15H10O5 |
| Molecular Weight: | 270.24 |
| Beilstein Registry Number: | 272683 |
| MDL number: | MFCD00017459 |
| PubChem Substance ID: | 24870246 |
Description
| Packaging | 100, 500 mg in glass btl |
| Application | The flavonoid component of Nepalese and Sino-Japanese crude drugs.1,2 Baicalein, a major flavone of Scutellariae baicalensis, inhibits the 12-lipoxygenase (12-LOX) pathway of arachidonic acid metabolism, which inhibits cancer cell proliferation and induces apoptosis. |
Properties
| assay | 98% |
| mp | 256-271 °C(lit.) |
| Gene Information | rat ... Alox15(81639), Alox5(25290) |
| mouse ... Hexa(15211) |
Safety
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
References
| Cited Reference | 1. Chem. Pharm. Bull. 39, 1051, (1991) |
| 2. Chem. Pharm. Bull. 38, 3488, (1990) | |
| Merck | Merck 13,944 |
| Beilstein | Beil. 18,V,4,569 |
